| San Diego Pregnancy Services | California | United States |
| San Fransisco County Department of Human Services | California | United States |
| San Joaquin County Human Services Agency - Adoptions | California | United States |
| San Luis Obispo County Department of Social Services | California | United States |
| San Mateo County Human Services Agency – Adoptions | California | United States |
| Santa Barbara County Department of Social Services | California | United States |
| Santa Clara County Social Services Agency Adoptions | California | United States |
| Santa Cruz County Human Resources Agency - Adoptions | California | United States |
| Sara Lee Foundation | Illinois | United States |
| Sarah's House Maternity Home | Texas | United States |
| Sauver le Darfour | | France |
| Save a Child Foundation | Utah | United States |
| Save Abandoned Babies Foundation | Illinois | United States |
| Sayap Ibu (Moedervleugel) | | |
| Scaife Foundations | Florida | United States |
| Schwab Charitable Fund | California | United States |
| Seattle International Adoptions | Washington | United States |
| Second Chance For Kids Program | | |
| Secretaría Nacional de Adopciones, Peru | | Peru |
| Secrétariat à l'adoption internationale (SAI) | Quebec | Canada |
| Seedlings Inc. | New Jersey | United States |
| Seeds of Hope, Ethiopia | Southern Nations - Nationalities and Peoples Region | Ethiopia |
| SEEK (Saving Eastern Europe's Kids) Inc. | Missouri | United States |
| Selamta Children Home | | |
| Sele Enat Mahiber, Ethiopia | Addis Abeba | Ethiopia |
| Semillas de Amor / Seeds of Love | Chimaltenango | Guatemala |
| Sense Resource Center, Inc. | Virginia | United States |
| Seoul Boystown orphanage | Seoul Special City | South Korea |
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